INTEGRATED METABOLOMICS AND NETWORK PHARMACOLOGY TO REVEAL THE MECHANISMS OF HYDROXYSAFFLOR YELLOW A AGAINST ACUTE TRAUMATIC BRAIN INJURY

Integrated metabolomics and network pharmacology to reveal the mechanisms of hydroxysafflor yellow A against acute traumatic brain injury

Traumatic brain injury (TBI) has become a leading cause of mortality, morbidity and disability worldwide.Hydroxysafflor yellow A (HSYA) is effective in treating TBI, but the potential mechanisms require further exploration.We aimed to reveal the mechanisms of HSYA against acute TBI by an integrated strategy combining metabolomics with network pharm

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